Every February, thousands of undie runners across the U.S. unite to support those affected by neurofibromatosis (NF), a group of genetic conditions that cause tumors to grow on nerves throughout the body. Cupid’s Undie Run returns to Denver on February 22, 2025, from 12–4 PM at Stoney’s Bar & Grill for an afternoon of drinking, dancing, and a mile(ish) fun run—all in your undies and all for charity.